Pharmaceutical compound



Patented Nov. 17, 1925.

UNITED STATES HANS HAHL, F ELBERFELD. GERMANY, FBIEDR. BAYER AND 00., 0F LEVERKU MANY.

ASSIGNOR TO FARBIENFABRIKEN VORM. BEN, NEAR OOLOGNE ON-THE-RHINE, GER- PHARMACEUTICAL coMrouNn.

No Drawing. Original'application filed December 10, 1924, Serial No. 755,059. Divided and this application filed June -27, 1925. Serial No. 40,103.

To all whom it may concern:

Be it known that I, HANS HAHL, a citizen of Germany, residing at Elberfeld, in the State of Prussia, Germany, have invented new and useful Improvements in Pharmaceutical Compounds, of which the following is a specification.

The present invention concerns the production of the hitherto unknown salts of 10 alkali metals of complex antimony com- .pounds being derived from mercapto-carboxylic acids e. g. the antimony sodium salt of thiosalicylic acid having most probably the formula:

s 0.1a coo Na sb s 0.1L- coo Na 0.11. coo Na They are slightly ellowish to whitish powders of a weak all raline reaction soluble in water, being valuable spirillocides.

In order to illustrate the new-process more fully the following example is given An aqueous solution of 20 parts by weight of thiosalicylic acid is neutralized with sodium carbonate and the resulting neutral hot solution is saturated with freshly precipitated antimony oxide 'Sb(OH) The liquid is filtered and the filtrate is evaporated 'to dryness. The sodium antimony salt is a ellowish powder soluble in hot .water with a weak alkaline reaction. By

treatment with Na s the antimony is precipitated.

The other alkali metal salts are prepared in an analogous manner.

The antimony sodium salt of the thioglycollic acid is for instance obtained by .mercapto-carboxylic acids,

. neutralizing the acid solution of the reaction product from thioglycollic acid and antimony oxide 'Sb O with sodium carbonate. It is a sli htly yellowish powder soluble in water 0 a weak alkaline reaction.

This is a division of the application Ser. No. 755,059, filed December 10, 1924.

I claim 1. The process of producing alkali metal salts of complex antimony compounds of a which process consists in treating the mercapto-carboxylic acid with an oxy derivative of the triva- .SCJ-LCOO-Na S s-o.Hi-coo-Na S-O.ILCOO-Na being a yellowish powder, soluble in water with a weakly alkaline reaction and being a valuable spirillocide, substantially as described.

In testimony whereof I have hereunto set my hand.

HANS HAHL. 

